Research
Mitochondrial research
Materials used to study mitochondrial signaling, biogenesis and electron transport.
MOTS-c, a mitochondrial-derived peptide
MOTS-c is a 16-amino-acid peptide encoded by a short open reading frame within the mitochondrial 12S rRNA gene. It was described in 2015 and has since become a reference material for research on how mitochondria signal to the rest of the cell.
Related tools
NAD+ supports electron transport through Complex I. Estrogen-related receptor agonists such as SLU-PP-332 are used to study transcriptional control of mitochondrial genes. Methylene blue can shuttle electrons in cell-free and cellular systems.